10+ GW of hyperscaler commitments. A 30M lb uranium deficit. Three investable layers across fleet operators, fuel cycle, and next-gen technology.
AI-driven power demand meets a supply-constrained nuclear fleet. Hyperscalers have contracted $50B+ in long-term PPAs, repricing existing plants as irreplaceable infrastructure.
Core Thesis
A multi-decade investment cycle spanning three layers — existing fleet operators (highest near-term visibility), fuel cycle companies (structural supply deficit), and next-gen technology (highest growth optionality). Nuclear is the only scalable 24/7 carbon-free solution for AI power.
Four publicly traded fleet operators control the US nuclear fleet. Their plants — operating at ~$30/MWh — are now selling 20-year contracts at $80-120/MWh to Big Tech.
| Buyer | Partner | Plant / Tech | Capacity | Term | Status |
|---|---|---|---|---|---|
| Microsoft | Constellation | TMI Unit 1 (restart) | 835 MW | 20 yr | Target 2027-28 |
| Meta | Constellation | Clinton (IL) | 1,121 MW | 20 yr | June 2027 |
| Meta | Vistra | Perry/Davis-Besse/BV + uprates | 2,609 MW | 20 yr | Late 2026 |
| Amazon | Talen | Susquehanna (PA) | 1,920 MW | 17 yr | Ramp 2026-32 |
| Meta | Oklo | New build (OH) | 1,200 MW | — | ~2030 |
| Kairos Power | SMR fleet | 500 MW | — | Through 2035 | |
| Amazon | X-energy | Xe-100 deployments | 5+ GW | — | By 2039 |
Primary mine supply covers ~75% of demand. Secondary sources are depleted. Every stage — conversion, enrichment, HALEU — faces capacity constraints. Spot uranium breached $100/lb in January 2026.
| Company | Ticker | Role | Production / Status | Key Catalyst |
|---|---|---|---|---|
| Kazatomprom | KAP | Largest miner (40% global) | 27.5-29K tU (2026) | Production discipline |
| Cameco | CCJ | #2 Western miner | 20M lbs (guidance) | Rising contract prices |
| NexGen Energy | NXE | Largest dev-stage project | 30M lbs/yr capacity | CNSC hearing Feb 2026 |
| Denison Mines | DNN | Wheeler River ISR | Construction-ready Q1 2026 | First Athabasca ISR |
| Uranium Energy | UEC | Largest US-focused | ISR ramp-up across 3 hubs | Burke Hollow ramp |
| Energy Fuels | UUUU | Only US conv. mill + REE | >1M lbs (2025) | Rare earth pivot |
| Centrus Energy | LEU | Only Western HALEU | 900 kg/yr (pilot) | $900M DOE expansion |
$6B+ in DOE funding. 10+ GW of hyperscaler commitments. First commercial units expected 2029-2032. But FOAK cost premiums and HALEU supply gaps remain key risks.
63-68 reactors under construction globally. China building half. COP28 pledge to triple capacity by 2050. US racing to match with NRC reform and SMR exports.
~62 GWe operating, ~43 GWe under construction. 10 new reactors approved April 2025 (~$27.5B). Target: 200 GW by 2035, 400-500 GW by 2050.
GBP 38B (~$51B) FID signed July 2025. Two EPR units. Largest single UK energy infrastructure commitment in decades.
EUR 50B program for 6 EPR2 reactors plus SMR pipeline. Rebuilding nuclear industrial base and workforce skills.
Barakah (UAE) delivered on time and on budget — rare in nuclear. APR-1400 positioned as default Western-aligned option.
From 8.2 GW to 22.5 GW by 2032. SMR LOI with France. 5+ domestic SMRs by 2033. Private sector participation enabled.
Rosatom: 46% enrichment, only commercial HALEU source. 6 reactors in Uzbekistan. Western decoupling underway but 5-7 years to close gap.
From fleet operators to uranium miners to SMR developers — the investable universe across the nuclear value chain.
| Company | Technology | Total Funding | Est. Valuation | Key Backers | IPO Outlook |
|---|---|---|---|---|---|
| X-energy | Xe-100 HTGR | $1.8B | $3-5B | Jane Street, ARK, Amazon | Strong candidate 2026-27 |
| Kairos Power | Molten salt-cooled | $500M+ | $2-4B | Google, DOE ARDP | Possible 2027+ |
| TerraPower | Natrium sodium fast | $1B+ | $4-6B | Bill Gates, DOE | Possible 2027+ |
| Commonwealth Fusion | Tokamak fusion | ~$3B | $5-6B | Nvidia, Google, Tiger | Venture-stage, 2028+ |
| Helion Energy | FRC fusion | $600M+ | $3-5B | Sam Altman, Microsoft | Venture-stage |
Build positions in fleet operators and fuel cycle. Watch SMR developers for de-risking catalysts. Size fusion as call options.
Research compiled February 2026. Not investment advice. See sources below.
Constellation Q3 2025 Results
Vistra Q3 2025 Results
BWX Technologies Q3 2025 Results
Cameco Production Update
Kazatomprom 1H2025 Results
UEC Q1 FY2026 Results
Energy Fuels Year-End Production
Talen Energy Amazon Relationship
Constellation TMI-Microsoft Restart
Meta 6.6 GW Nuclear Announcement
Vistra-Meta Nuclear Agreements
Talen-Amazon $18B Nuclear PPA
Google-Kairos Power Agreement
Oklo-Meta 1.2 GW Agreement
Sprott Uranium Outlook 2026
Kazatomprom 2026 Production Cut
Cameco Supply & Demand
World Nuclear Fuel Report 2025
Centrus $900M Expansion Award
Urenco USA Enrichment Milestones
ADVANCE Act — NRC
NRC Part 53 Rulemaking
EO 14300 NRC Reform Actions
Russian Uranium Import Ban
DOE Loan Programs Office
World Nuclear Power Reactors — WNA
Economics of Nuclear Power — WNA
IEA Nuclear Investment Outlook
Lazard LCOE+ June 2025
IEA AI Data Center Demand